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目的探讨糖尿病足的截肢相关的危险因素。方法对住院的219例糖尿病足患者临床资料进行回顾分析。结果截肢组与非截肢组HBA1C(10.42±1.72)%,(8.26±2.08)%(P<0.05);下肢血管病变分别为72例(98.63%)、120例(82.19%)(P<0.05);神经病变66例(90.41%)、123例(84.24%)(P<0.05)。多因素分析有意义的变量为下肢血管病变、年龄、收缩压、CRP(P<0.05)。结论糖尿病足截肢与病程、年龄有密切的关系,糖化血红蛋白、高血压、糖尿病下肢血管病变、C反应蛋白是糖尿足截肢的危险因素。
Objective To investigate the amputation related risk factors of diabetic foot. Methods The clinical data of 219 patients with diabetic foot hospitalized were retrospectively analyzed. Results HBA1C (10.42 ± 1.72)%, (8.26 ± 2.08)% (P <0.05) in the amputation group and the non-amputation group were 72 cases (98.63%) and 120 cases (82.19%) in the lower limbs respectively (P <0.05) ; 66 cases of neuropathy (90.41%), 123 cases (84.24%) (P <0.05). Multivariate analysis of meaningful variables for lower extremity vascular disease, age, systolic blood pressure, CRP (P <0.05). Conclusion Diabetic foot amputation is closely related to the course of disease and age. Glycated hemoglobin, hypertension, diabetic lower extremity vascular disease and C-reactive protein are the risk factors of diabetic foot amputation.