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应用组织学和免疫组织化学方法,观察大鼠肝部分切除后1、2、8、7和14天期间甲状腺滤泡上皮细胞的变化。假手术后滤泡上皮细胞分泌机能有所降低,可能与应激反应有关,肝大部切除后,滤泡上皮细胞明显增高,胞质内胶体小滴的数量和T_3、T_4免疫反应物的量均增加。这些变化以术后2—3天最明显,到术后第14天渐趋正常。提示肝大部切除后,特别是术后2—3天,滤泡上皮细胞分泌活动增进。肝小部切除后,滤泡上皮细胞的变化特点和趋势与肝大部切除的相似,但变化程度较轻。本文结果说明,甲状腺滤泡上皮细胞的变化与肝再生间存在着密切的关系。
Histological and immunohistochemical methods were used to observe the change of thyroid follicular epithelial cells at 1, 2, 8, 7 and 14 days after partial hepatectomy in rats. After sham operation, the secretion of follicular epithelial cells decreased, which may be related to the stress response. After the majority of hepatic resection, the follicular epithelial cells were significantly increased, the number of colloidal droplets and the amount of T_3 and T_4 immunoreactive Increase. These changes were most pronounced 2-3 days after surgery and became normal on the 14th day after surgery. Prompt liver resection, especially after 2-3 days, follicular epithelial cell secretory activity increased. After the hepatectomy, the characteristics and trends of follicular epithelial cells were similar to those of resection of the liver, but the changes were mild. The results of this paper show that changes in thyroid follicular epithelial cells and liver regeneration are closely related.