论文部分内容阅读
为探讨宫颈湿疣的诊断及其与宫颈癌发生的关系，作者对４８例宫颈湿疣、４６例宫颈癌进行了细胞学、组织病理学、阴道镜、免疫组化及ＨＰＶ—ＤＮＡ相关序列及超微结构检查。细胞学诊断宫颈湿疣的阳性率为７０．８３％。３９例外阴、阴道尖锐湿疣中，２１例经阴道镜检查并活检证实有宫颈湿疣。单纯宫颈湿疣免疫组化检查ＨＰＶ抗原的检出率为６３．１５％。宫颈湿疣及宫颈癌ＨＰＶ—ＤＮＡ基因相关序列的检出率分别为４２１％及８５％。依靠细致的妇科检查，对外阴、阴道湿疣及宫颈刮片异常的患者常规作阴道镜检查及其引导下的宫颈活检，不难作出宫颈湿疣的诊断。
In order to explore the diagnosis of cervical condyloma and its relationship with cervical cancer, the author of 48 cases of cervical condyloma and 46 cases of cervical cancer cytology, histopathology, colposcopy, immunohistochemistry and HPV-DNA-related sequences and ultrastructure Structural inspection. The positive rate of cytology diagnosis of cervical condyloma was 70.83%. 39 cases of vulva, vaginal condyloma acuminata, 21 cases of colposcopy and biopsy confirmed cervical condyloma. The detection rate of HPV antigen in cervical spondylosis was 63.15%. The detection rates of HPV-DNA gene-related sequences in cervical condyloma and cervical cancer were 421% and 85% respectively. Rely on detailed gynecological examination of the vulva, vaginal condyloma and cervical smear abnormalities in patients with conventional colposcopy and cervical biopsy under its guidance, is not difficult to make a diagnosis of cervical condyloma.