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目的:观察福辛普利与吲达帕胺联合治疗高血压合并心力衰竭的疗效。方法:将88例高血压合并心力衰竭患者随机分为联合用药组和对照组,评价治疗前后血压、心功能等指标变化。结果:治疗8周后联合用药组总疗效率高于对照组(P<0.05)、血压下降更显著(P<0.01)、LVEF、E/A提高更为明显(P<0.05)。结论:福辛普利与吲达帕胺联合治疗高血压合并心力衰竭临床症状改善更明显,血压控制更理想,是一种有益的治疗选择。
Objective: To observe the curative effect of fosinopril and indapamide in the treatment of hypertension complicated with heart failure. Methods: Eighty-eight patients with hypertension complicated with heart failure were randomly divided into combined treatment group and control group to evaluate the changes of blood pressure and cardiac function before and after treatment. Results: After 8 weeks of treatment, the total effective rate of the combination group was higher than that of the control group (P <0.05). The blood pressure decreased more significantly (P <0.01) and the LVEF and E / A increased more significantly (P <0.05). Conclusion: The combination of fosinopril and indapamide can improve the clinical symptoms of hypertension and heart failure more obviously and control the blood pressure better, which is a beneficial treatment option.