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目的探讨儿童生长发育与重症手足口病的相关性。方法采用整群随机抽样的方法,调查2010～2012年期间龙岗区发生的0～72月龄手足口病重症病例42例和门诊病例83例,计算研究对象的身高、体重标准百分位水平,采用WHO推荐的儿童生长发育标准(2007版),评价研究对象的发育状况。结果两组年龄别身高标准百分位水平差异没有统计学意义(t=-0.58,P=0.56),但年龄别体重标准百分位水平存在统计学差异(t=-3.23,P=0.00);两组儿童的低体重情况的构成比不同,差异有统计学意义(χ2=4.07,P=0.04);两组儿童的生长发育迟缓及消瘦情况的构成比相同,差异没有统计学意义(生长发育迟缓:χ2=1.08,P=0.30;消瘦:χ2=1.04,P=0.75)。结论重症手足口病的发生与儿童自身的近期营养状况有关,对于重症手足口病的防治可能可以从营养学的角度入手。
Objective To investigate the correlation between children’s growth and development and severe hand-foot-mouth disease. Methods A cluster random sampling method was used to investigate 42 cases of hand-foot-mouth disease and 83 out-patient cases from 0 to 72 months in Longgang District from 2010 to 2012. The height and weight percentile level, Adopted the WHO Recommended Child Growth and Development Standard (2007 Edition) to evaluate the development status of the research object. Results There was no significant difference in the standard height percentile between the two groups (t = -0.58, P = 0.56), but there was a significant difference in the age percentile weight percentile (t = -3.23, P = 0.00) ; The constitutional ratio of low-weight cases in the two groups was different, the difference was statistically significant (χ2 = 4.07, P = 0.04); the two groups of children had the same composition ratio of growth retardation and emaciation, the difference was not statistically significant Developmental delay: χ2 = 1.08, P = 0.30; wasting: χ2 = 1.04, P = 0.75). Conclusion The occurrence of severe hand-foot-mouth disease is closely related to the nutritional status of children. The prevention and treatment of severe hand-foot-mouth disease may be from the perspective of nutrition.