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目的对比分析中西医疗法与中西医序贯疗法在糖尿病肾病治疗中的临床效果。方法选择我院接受治疗的糖尿病肾病患者80例作为临床研究对象,按入院先后依次编号01~80,以双号患者为对照组,单号患者为试验组。对照组40例患者应用常规中西医治疗,试验组40例患者接受应用中西医序贯疗法,分析比较两组患者经不同治疗方法治疗后的肾功能情况以及不良反应发生情况。结果两组患者在不同方法治疗后,试验组患者的总不良反应发生率显著低于对照组的总不良反应发生率;对照组患者的血肌酐值以及24小时尿白蛋白值显著高于观察组患者的血肌酐值、血尿素氮值以及24小时尿白蛋白值,差异在统计学上均有意义(P<0.05)。结论应用中西医序贯疗法治疗糖尿病肾病患者,可更安全有效的提高肾功能,值得在临床推广应用。
Objective To compare the clinical effects of Chinese and western medicine and sequential therapy of Chinese and Western medicine in the treatment of diabetic nephropathy. Methods Eighty patients with diabetic nephropathy treated in our hospital were selected as clinical research subjects. The patients were numbered 01-80 in order of admission, double-numbered patients as control group and single-number patients as experimental group. Forty patients in the control group were treated with conventional Chinese and western medicine. Forty patients in the experimental group received sequential Chinese and Western medicine. The renal function and adverse reactions of the two groups after treatment were compared. Results The incidence of adverse reactions in the two groups was significantly lower than that in the control group after treatment by different methods. The serum creatinine and 24-hour urinary albumin in the control group were significantly higher than those in the observation group The patient’s serum creatinine, blood urea nitrogen and 24-hour urine albumin values, differences were statistically significant (P <0.05). Conclusion The application of sequential therapy of Chinese and Western medicine in patients with diabetic nephropathy can be more safely and effectively improve renal function, it is worth in the clinical application.