本文目的在于检验在排除其它可能的混杂因素(同母亲的吸烟习惯和儿童行为问题相关的因素)之后,妊娠前后母亲吸烟与学龄儿破坏行为的相关程度。方法:通过对1265例同期出生的新西兰儿童15年追踪研究,获得了以下资料:(1)妊娠前后每天吸烟的量;(2)依据母亲和老师报告对儿童破坏行为(包括品行问题和注意缺陷行为)的测量;(3)混杂因素如家庭、社会、父母及其它有关因素。结果:在调整混杂因素之前,发现母亲妊娠前后吸烟同儿童行为问题显著增加有关;母亲每天吸烟超过20支的儿童平均行为问题评分比母亲不吸烟儿童高0.16～0.56个标准差。采用回归法,针对下列因素对此结果进行调查。(1)妊娠与妊娠后吸烟的关系;(2)主要混杂因素。回归结果提示:即使调整了一系列混杂因素,妊娠期间母亲吸烟仍使儿童行为问题有小幅度增加,并且有统计学意义。母亲每天吸烟超过20支的儿童行为问题平均得分比非吸烟母 The purpose of this paper is to examine the correlation between maternal smoking and school-age disruptive behaviors before and after pregnancy, excluding other possible confounders (factors related to mother’s smoking habits and child behavior problems). METHODS: The follow-up study of 1265 New Zealand children born in the same period of time obtained the following data: (1) the amount of daily smoking before and after pregnancy; (2) the data on mothers ’and teachers’ reports of child vandalism (including conduct problems and attention deficits Behavior) measurements; (3) confounding factors such as family, community, parents and other related factors. Results: Before adjusting for confounding factors, it was found that maternal smoking had a significant increase in behavior problems before and after pregnancy. The average behavioral problems scores of mothers who smoked more than 20 cigarettes per day were 0.16 ~ 0.56 standard deviations higher than those of non-smokers. Using regression, the results were investigated for the following factors. (1) the relationship between pregnancy and smoking after pregnancy; (2) the main confounding factors. The regression results suggest that even with a mix of confounders adjusted, mothers smoking during pregnancy continued to have a small increase in children’s behavioral problems and was statistically significant. Mothers smoked more than 20 children a day behavioral problems average score than non-smoking mothers