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目的探讨复发性和转移性腹膜后脂肪肉瘤的治疗方法。方法回顾性分析25例复发性和转移性腹膜后脂肪肉瘤作积极外科治疗,辅以放疗和化疗的临床资料。结果除6例仍在2年内治疗中,余19例中18例生存3年以上,10例生存5年以上,5年生存率为52.6%。手术的次数和有无合并脏器切除与生存无明显关系。完全切除能得到较好的预后,而部分切除结合放疗和化疗能也得到较满意的效果。手术加放疗是最满意的结合。结论复发性和转移性腹膜后脂肪肉瘤的预后差与完全切除肿瘤及部分切除的肿瘤辅以放疗和化疗有关
Objective To investigate the treatment of recurrent and metastatic retroperitoneal liposarcoma. Methods Retrospective analysis of 25 cases of recurrent and metastatic retroperitoneal liposarcoma for active surgical treatment, supplemented by radiotherapy and chemotherapy clinical data. Results In addition to 6 cases still being treated within 2 years, 18 of the remaining 19 cases survived for more than 3 years, 10 cases survived more than 5 years, and the 5-year survival rate was 52.6%. The number of operations and the presence or absence of excision of the organs were not significantly related to survival. Complete resection can get a better prognosis, and partial resection combined with radiotherapy and chemotherapy can also get satisfactory results. Surgery plus radiotherapy is the most satisfactory combination. Conclusion The poor prognosis of recurrent and metastatic retroperitoneal liposarcoma is related to complete resection of the tumor and partial resection of the tumor, supplemented by radiotherapy and chemotherapy.