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目的：探讨移植肾膜性肾病（ＭＧＮ）和膜增殖性肾炎（ＭＰＧＮ）的病理、临床特征及预后。方法：分析移植肾穿刺活检病理诊断及临床资料。结果：检出５例ＭＧＮ及４例ＭＰＧＮ，病理特征与普通肾脏病患者相同，不同之处为３例ＭＧＮ及４例ＭＰＧＮ同时存在慢性排异反应（ＣＲ）表现，１例ＭＰＧＮ伴有ＣＲ及急性排异反应（ＡＲ），并于术后３５个月失功。两类肾炎均以肾病综合征为主要表现，伴早期血肌酐异常，雷公藤多甙能有效改善蛋白尿。结论：移植肾ＭＰＧＮ及ＭＧＮ多伴有ＣＲ，预后欠佳，雷公藤多甙的治疗结果提示该药有良好前景。
Objective: To investigate the pathology, clinical features and prognosis of renal allograft nephropathy (MGN) and proliferative glomerulonephritis (MPGN). Methods: The pathological diagnosis and clinical data of transplanted renal biopsy were analyzed. Results: Five cases of MGN and four cases of MPGN were detected. The pathological features were the same as those of common nephrotic patients except for 3 cases of MGN and 4 cases of MPGN presenting with chronic rejection (CR), 1 case of MPGN with CR and Acute rejection (AR), and after 35 months of failure. Both types of nephritis are nephrotic syndrome as the main performance, with early abnormal serum creatinine, Tripterygium glycosides can effectively improve proteinuria. CONCLUSION: MPGN and MGN mostly accompany with CR, the prognosis is poor. The results of treatment with tripterygium glycosides suggest that this medicine has good prospects.