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目的:探讨消化性溃疡和胃炎患者应用尿囊素铝颗粒进行治疗的疗效及安全性。方法:以我院2014年7月至2015年7月收治的116例患者(62例消化性溃疡患者和54例胃炎患者)为研究对象,将其随机分为两组,观察组31例消化性溃疡患者和27例胃炎患者采用尿囊素铝颗粒治疗,对照组31例消化性溃疡患者和27例胃炎患者采用替普瑞酮治疗,观察和比较两组患者的治疗效果。结果:治疗一个月后,观察组患者的消化性溃疡和胃炎愈合率分别为90.32%和88.89%,对照组患者的消化性溃疡和胃炎愈合率分别为70.97%和70.37%,观察组患者的消化性溃疡和胃炎愈合率明显高于对照组(P<0.05)。观察组患者中,4例患者出现不良反应,持续2~3 d后未经处理自行消失。结论:消化性溃疡和胃炎患者应用尿囊素铝颗粒进行治疗,效果安全可靠。
Objective: To investigate the efficacy and safety of allantoin granule in patients with peptic ulcer and gastritis. Methods: A total of 116 patients (62 patients with peptic ulcer and 54 patients with gastritis) admitted to our hospital from July 2014 to July 2015 were randomly divided into two groups. The observation group consisted of 31 patients with digestive Ulcer patients and 27 cases of gastritis patients treated with allantoin aluminum particles in the control group of 31 patients with peptic ulcer and 27 cases of gastritis treated with teprenone treatment was observed and compared two groups of patients. Results: The healing rate of peptic ulcer and gastritis were 90.32% and 88.89% respectively in the observation group and 70.97% and 70.37% respectively in the control group. The digestion rate of peptic ulcer and gastritis in the control group was significantly lower than that in the observation group The healing rate of ulcer and gastritis was significantly higher than that of the control group (P <0.05). In the observation group of patients, 4 patients showed adverse reactions, continuing 2 to 3 d disappeared without treatment. Conclusion: The treatment of patients with peptic ulcer and gastritis with allantoin aluminum particles is safe and reliable.