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白血病时神经系统并发症发病率各个作者的报告有所不同,Kimmelstiel(1943)统计为6％;Schwab(1953)20.5％;Кадырова和Рузинова(1963)71～72％。白血病的神经系统受累率逐年有增高趋势,这可能与白血病治疗方法的改进,患者生存期限逐渐延长,以及诊断准确率逐步提高有关。有些白血病患者生前并无神经症状,而尸检时却发现神经系统有病理改变,Leidler等曾报告白血病死亡病例在尸检时发现83％有神经系统罹患,而生前仅有35％出现神经症状和体征。
The incidence of neurologic complications in leukemias varies among authors, Kimmelstiel (1943) 6%; Schwab (1953) 20.5%; Кадырова and Рузинова (1963) 71-72%. The leukemia neurological involvement rate has increased year by year, which may be related to the improvement of leukemia treatment methods, the patient’s life span is gradually extended, and the diagnostic accuracy rate gradually increased. Some leukemia patients had no neurological symptoms during their lifetime, but autopsy found pathological changes in the nervous system. Leidler et al. Reported that death from leukemia was found in 83% of autopsy patients with neurological diseases and only 35% of them had neurological symptoms and signs during their lifetime.