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自从1983年澳大利亚学者Warren和Marshall首次从慢性活动性胃炎患者胃粘膜活检标本中成功分离出幽门螺杆菌(Hp)以来,Hp感染与胃、十二指肠疾病的相关性日益受到广泛重视。我们通过快速尿素酶试验(RUT)、粘膜组织检查、~(13)C或~(14)C呼气试验(~(13)C-UBT、~(14)C-UBT)、粪便Hp抗原(HpSA)检测4种方法联合检测180例患者,旨在了解中、重度萎缩性胃炎患者Hp感染情况,探讨多种方法联合检测的可行性和必要性。
Since the first time that H. pylori (Hp) was successfully isolated from mucosal biopsy specimens of chronic active gastritis by Australian scholar Warren and Marshall in 1983, the relationship between Hp infection and gastric and duodenal diseases has been paid more and more attention. We evaluated the effects of Hp antigens on stool samples by rapid urease test, mucosal examination, ~ (13) C or ~ (14) C breath test (~ (13) C-UBT and ~ (14) C-UBT) HpSA) four methods combined detection of 180 patients, in order to understand the Hp infection in patients with moderate and severe atrophic gastritis, explore the feasibility and necessity of a variety of methods combined detection.