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作者选择26只健康豚鼠,采用特殊装置,将2μl人造内淋巴液在0.5～4分钟内注入内淋巴间隙,同时测定内淋巴直流电位和内、外淋巴压力的变化,以进一步阐明内、外淋巴压力的相互关系及两者压力的差别。另选5只豚鼠杀死后作组织学研究。结果发现,在进行内淋巴灌注时,实验动物的内、外淋巴压力同时发生动力学变化,两者压力的增加几乎相同。在灌注后不久,内、外淋巴压力在统计学上无显著差别。(本研究中所用的测定方法分辨率为±13.33Pa)。组织学研究的结果表明,在灌注2ml人造内淋巴后,前庭膜出现轻度膨胀,球囊则呈明显膨胀,但未发现膜迷路破坏的迹
The author chose 26 healthy guinea pigs and used special device to inject 2μl of artificial endolymph into the endolymphatic space in 0.5-4 minutes. Meanwhile, the changes of endolymphatic DC potential and endolymphatic pressure were measured to further clarify the expression of endolymph and perilymph The relationship between the pressure and the pressure difference between the two. The other five guinea pigs were sacrificed for histological studies. The results showed that, in the endolymphatic perfusion, the experimental animals, both external and internal lymphatic pressure at the same time dynamic changes in both pressure increases are almost the same. Shortly after perfusion, there was no statistically significant difference in internal and external lymphatic pressure. (The assay used in this study has a resolution of ± 13.33 Pa). Histological studies showed that there was a slight swelling of the vestibular membrane and a marked swelling of the balloon after infusion of 2 ml of artificial endolymph, but no trace of labyrinthine membrane destruction was found