季也蒙念珠菌皮肤肉芽肿临床治疗较为困难。原位激光免疫疗法是一种由局部光热联合免疫佐剂组成的新型治疗方法。本例研究中,我们首次将原位激光免疫疗法应用于一例伊曲康唑口服12个月治疗无效的季也蒙念珠菌皮肤肉芽肿患者。激光免疫疗法一个疗程为10周,10周内5%咪喹莫特每两天外涂一次,在第14、28、42和56天时采用808 Season also Candida skin granuloma clinical treatment more difficult. In situ laser immunotherapy is a novel therapeutic approach consisting of local photothermal combined adjuvant. In this case study, for the first time, we applied in situ laser immunotherapy to a patient with candidal candidal cutaneous candidiasis of Seychelles treated with itraconazole for 12 months. One course of laser immunotherapy was 10 weeks, and 5% imiquimod was topically applied every two days in 10 weeks and 808 at days 14, 28, 42 and 56