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封面故事 :血栓性紫癫的形成原因因血细胞减少、血栓形成而出现的紫癫的形成原因 ,自这种病变 192 4年被首次描述以来一直不为人们所知。现在 ,科学家采用定位克隆方法 ,发现与这种疾病有关的基因是ＡＤＡＭＴＳ锌金属蛋白酶家族的一个新成员。新发现的ＡＤＡＭＴＳ13蛋白酶会
Cover story: Causes of thromboembolism The formation of purple epilepsy due to cytopenias and thrombosis has never been known since this condition was first described in 1944. Scientists now use site-directed cloning to find that the genes involved in the disease are a new member of the ADAMTS family of zinc metalloproteases. The newly discovered ADAMTS13 protease would