γ 氨基丁酸 (GABA)是中枢神经系统 (CNS)内主要的抑制性神经递质 ,通过位于脑内的GABA受体发挥抑制性作用 ,其受体功能异常与特发性癫痫的发生密切相关。当脑内GABA含量降低而兴奋性神经递质 (如谷氨酸 )水平升高时就可能发生癫痫。目前使用的数种较有效的抗癫痫新药 ,虽然在 GABA is the major inhibitory neurotransmitter in the central nervous system (CNS). It exerts an inhibitory effect through GABA receptors located in the brain, and its receptor dysfunction is closely related to the occurrence of idiopathic epilepsy . Epilepsy can occur when the levels of GABA in the brain decrease and levels of excitatory neurotransmitters, such as glutamate, increase. There are several more effective antiepileptic drugs currently in use though