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目的探讨小剂量红霉素治疗早产儿喂养不耐受的疗效。方法将54例出现喂养不耐受的早产儿随机分为治疗组31例和对照组23例。对照组给予保暖,抗感染,维持水电解质平衡,营养支持和对症治疗,治疗组在常规冶疗基础加小剂量红霉素3-5mg/kg.d,静脉滴注,1次/日,疗程5-7天。结果治疗组总有效率为83.87%,较对照组总有效率43.78%高(P<0.01),差异有统计学意义。结论小剂量红霉素治疗早产儿喂养不耐受有显著疗效,未见不良反应发生。
Objective To investigate the efficacy of low-dose erythromycin in treating intolerance in preterm infants. Methods 54 cases of preterm infants with feeding intolerance were randomly divided into treatment group (n = 31) and control group (n = 23). The control group was given warm, anti-infection, maintain water and electrolyte balance, nutritional support and symptomatic treatment, the treatment group in the conventional treatment plus small doses of erythromycin 3-5mg / kg.d, intravenous drip, 1 / day, treatment 5-7 days. Results The total effective rate in the treatment group was 83.87%, which was 43.78% higher than that in the control group (P <0.01). The difference was statistically significant. Conclusion Low-dose erythromycin in treating premature infants with intolerance has a significant effect, no adverse reactions occurred.