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川芎嗪(四甲吡嗪 Tetramethyl Pyra-zine)系川芎中的一种有效生物碱,药理研究证明它具有改善微循环的作用。临床上使用川芎嗪治疗急性缺血性脑血管病有肯定的疗效。至今尚未见到急性脑血栓形成的病人使用川芎嗪治疗后甲皱微循环的观察报告。为了观察川芎嗪治疗急性脑血栓形成病人甲皱微循环的变化,对比偏瘫病人健、瘫侧甲皱微循环的变化以及探讨急性脑血栓形成病人甲皱微循环检查的临床意义,我们观察了28例川芎嗪治疗的急性脑血栓形成病人的双侧甲皱微循环,其结果如下:
Ligustrazine (Tetramethyl Pyra-zine) is an effective alkaloid in Rhizoma Chuanxiong. Pharmacological studies have shown that it has the effect of improving microcirculation. Clinical use of tetramethylpyrazine for the treatment of acute ischemic cerebrovascular disease has a positive effect. To date, observations on nailfold microcirculation after treatment with ligustrazine have not been seen in patients with acute cerebral thrombosis. In order to observe the changes of nailfold microcirculation in patients with acute cerebral thrombosis treated with ligustrazine, and to compare the changes in the hepatic and creatine microcirculation of patients with hemiplegia and to explore the clinical significance of nailfold microcirculation in patients with acute cerebral thrombosis, we observed 28 Cases of acute cerebral thrombosis in patients treated with tetramethylpyrazine have bilateral nailfold microcirculation. The results are as follows: