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颈动脉系的夹层动脉病(CAD)是青年脑卒中的常见原因之一,在脑卒中患者中患病率约占20%,其中颈内动脉夹层动脉病(ICAD)占70%~80%。许多因素如高血压病、糖尿病、创伤等都与其有关。ICAD多表现为同侧颈部疼痛或头痛、Horner综合征及脑缺血。磁共振血管造影为其首选检查方法。ICAD相对预后良好。抗凝与抗血小板药物在其急性期治疗及二级预防中仍存在争议。文中就ICAD的流行病学、临床表现、病理生理、治疗及预后的研究进展进行综述。
The carotid artery dissecting artery disease (CAD) is one of the most common causes of stroke in young people. The prevalence rate is about 20% in stroke patients, of which 70% to 80% are carotid artery dissecting arterial disease (ICAD). Many factors such as hypertension, diabetes, trauma and so on are related to it. ICAD manifested as ipsilateral neck pain or headache, Horner syndrome and cerebral ischemia. Magnetic resonance angiography as the preferred method of examination. ICAD relatively good prognosis. Anticoagulation and antiplatelet drugs are still controversial in the treatment of their acute phase and secondary prevention. This article reviews the epidemiology, clinical manifestations, pathophysiology, treatment and prognosis of ICAD.