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为观察模拟失重对肠系膜动脉血管反应性的影响，采用尾部悬吊大鼠模型模拟失重，并利用离体动脉环测定血管反应性的变化。结果显示：悬吊２周大鼠肠系膜前动脉环对ＫＣｌ（１０～８０ｍｍｏｌ／Ｌ）与苯肾上腺素（１０－１０～１０－４ｍｏｌ／Ｌ）的收缩反应明显降低，对硝普钠（１０－１０～１０－４ｍｏｌ／Ｌ）的舒张反应无明显改变。提示：尾部悬吊明显降低了大鼠肠系膜动脉的收缩能力，而对动脉平滑肌的舒张能力无明显影响
To observe the effects of simulated weightlessness on mesenteric arterial reactivity, a tail-suspended rat model was used to simulate weightlessness and the changes of vascular reactivity were measured using isolated arterial rings. The results showed that the contraction of KMC (10 ~ 80mmol / L) and phenylephrine (10 ~ 10 ~ 10 ~ 4mol / L) 10 ~ 10-4mol / L) no significant change in the relaxation response. TIP: Tail suspension significantly reduced the contractility of rat mesenteric artery, but had no significant effect on the diastolic capacity of arterial smooth muscle