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以高脂饲料诱导高脂血症小鼠模型,研究了蒺藜皂苷的调血脂作用。研究表明:蒺藜皂苷能降低实验性高脂血症小鼠血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)及肝脏胆固醇、甘油三酯的含量;在灌胃蒺藜皂苷的同时继续喂食高脂饲料,能有效地阻止血清胆固醇、低密度脂蛋白胆固醇(LDL-C)的升高,同时能降低肝脏胆固醇、甘油三酯的含量,提高肝脏超氧化物歧化酶的(SOD)的活性。
Hyperlipidemia was used to induce hyperlipidemia in a mouse model and the lipid-regulating effects of triterpene saponins were studied. Studies have shown that triterpene saponins can reduce serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and liver cholesterol and triglyceride levels in experimental hyperlipidemic mice; Feeding high-fat diets can effectively prevent the increase of serum cholesterol and low-density lipoprotein cholesterol (LDL-C), at the same time, it can reduce liver cholesterol and triglyceride levels, and increase the level of superoxide dismutase (SOD) in the liver. active.