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１ 引 言慢性肾功能衰竭时，钙磷代谢失调主要表现为血磷升高、血钙降低，并通过刺激甲状旁腺分泌甲状旁腺素（ｐａｒａｔｈｒｏｉｄｈｏｒｍｏｎｅ，ＰＴＨ）增多，导致肾性骨营养不良症的发生［１］。因此防治肾性骨病的关键是维持尽可能正常的血钙、血磷浓度。我们应用新
1 Introduction Chronic renal failure, calcium and phosphorus metabolic disorders mainly as elevated serum phosphorus, decreased serum calcium and parathyroid hormone secretion by stimulating parathyroid hormone (parathyroid hormone, PTH) increased, leading to renal osteodystrophy Occurs [1]. Therefore, the key to prevention and treatment of renal osteodystrophy is to maintain the normal blood calcium and serum phosphorus levels as much as possible. We apply new