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目的:探讨病毒性肝炎不同病程患者血液中Alb、CHE、TH含量的变化及临床意义。方法:应用放射免疫竞争技术检测252例病毒性肝炎患者血液中Alb、CHE、FT4、FT3、TG、TSH含量。结果:急性肝炎组和慢性肝炎轻度组Alb、CHE、FT4、FT3、TG、TSH含量与正常对照组比较无统计学差异(P>0.05),慢性肝炎中度组,重度组患者与正常对照组比较有统计学差异(P<0.05),肝硬化组患者结果与正常对照组比较有统计学差异(P<0.01)。结论:急性与慢性肝炎患者随病情稳定TH水平恢复正常水平,重度肝炎和肝硬化患者TH和ALB、CHE结果异常改变增多,恢复较差,通过检测血液ALB、CHE、和TH可评价病毒性肝炎预后与转归。
Objective: To investigate the changes and clinical significance of Alb, CHE and TH in the blood of patients with different stages of viral hepatitis. Methods: The contents of Alb, CHE, FT4, FT3, TG and TSH in 252 patients with viral hepatitis were detected by radioimmunoassay. Results: The levels of Alb, CHE, FT4, FT3, TG and TSH in acute hepatitis group and chronic mild hepatitis group were not significantly different from those in normal control group (P> 0.05) (P <0.05). There was a significant difference between the two groups (P <0.01). Conclusion: Patients with acute and chronic hepatitis returned to normal levels with stable disease status. The abnormal changes of TH, ALB and CHE in patients with severe hepatitis and cirrhosis increased and recovered poorly. Viral hepatitis could be evaluated by detecting blood ALB, CHE, and TH Prognosis and prognosis.