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目的:探讨影响重型肝炎(重肝)预后的因素。方法:本文总结了207例重型病毒性肝炎资料。结果:(1)重肝好发年龄主要分布于30～50岁,年龄越大,死亡率越高,老年患者病死率达71.4％;(2)单纯HBV感染是重肝的主要病因,占70.5％,其病死率49.65％,而重叠病毒感染(HBV+HCV和/或HBV+HEV)均明显加重病情,病死率达55.56％和53.65%;(3)重肝早期治疗有效率达65.4%,而中晚期疗效差,有效率34.8％和11.3％;(4)重肝按脑病型、腹水型、混和型及其它型分型,各型治愈好转率有明显差异,分别为25％、42％、7%和63％;(5)并发症多少与转归明显关联,0～1种存活率46%,2～3种13.3％,4～5种5.4%;(6)重肝患者常伴有胆结石胆囊炎(12.6%)、糖尿病(Ⅱ型)(4.8%)、胰腺炎(0.7％)等。结论:年龄大小,病因不同,临床类型不同,并发症多少及伴随疾患的有无,均会影响重肝转归。
Objective: To explore the factors affecting the prognosis of severe hepatitis (severe liver). Methods: This article summarizes 207 cases of severe viral hepatitis data. Results: (1) The prevalence of severe hepatitis was mainly distributed between 30 and 50 years old. The older the mortality was, the higher the mortality rate was 71.4%. (2) HBV infection was the main cause of severe liver disease, accounting for 70.5 %, The case fatality rate was 49.65%, while the overlap virus infection (HBV + HCV and / or HBV + HEV) were significantly aggravated, the mortality rate reached 55.56% and 53.65%; (3) The effective rate of early liver treatment was 65.4% While the curative effect in the middle and late period was poor with effective rates of 34.8% and 11.3% respectively. (4) Hepatic disease was significantly different according to encephalopathy type, ascites type, mixed type and other types, with 25% and 42% , 7% and 63%, respectively; (5) The number of complications was significantly associated with the outcome of the treatment, 0 ~ 1 survival rate 46%, 2 ~ 3 13.3%, 4 ~ 5 5.4% There are cholecystolithiasis (12.6%), diabetes (type Ⅱ) (4.8%), pancreatitis (0.7%) and so on. Conclusion: Age, different etiologies, different clinical types, the number of complications and the presence or absence of the disease all affect the prognosis of HCC.