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1957年以来,世界卫生组织狂犬病专家委员会就推荐对于高危险性人群如狂犬病毒实验室工作人员、兽医、狗主等的狂犬病感染前免疫接种。最先用于人类感染前免疫试验的是山浦氏、鸡胚或鸭胚狂犬病疫苗。目前美国推荐应用的有3剂或4剂鸭胚疫苗,并在机体出现阳性应答前14周或者认为必要时作一剂加强免疫。 1972年,Fuenzalida研究了隔天接种2毫升乳鼠脑疫苗三剂的结果,这个加速的方案
Since 1957, the WHO Committee of Rabies Experts has recommended immunizations against pre-rabies infections in high-risk groups such as rabies virus laboratory staff, veterinarians, dog owners and the like. The first vaccine used in human immunodeficiency trials was the Pura, Chick embryo or duck embryo rabies vaccine. At present, three or four duck embryo vaccines recommended for use in the United States are boosted in the first 14 weeks before the body develops a positive response or when necessary. In 1972, Fuenzalida studied the results of three doses of 2 ml neonatal brain vaccine administered the next day. This accelerated protocol