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目的观察氨氯地平联合缬沙坦治疗高血压的临床疗效。方法选取医院2014年7月-2015年7月收治的高血压患者参102例,随机分为观察组和对照组各51例。对照组给予缬沙坦治疗,观察组在对照组治疗基础上加用氨氯地平治疗,将2组患者治疗后的降压效果进行对比。结果治疗4周后,观察组总有效率为98.04%明显高于对照组的86.27%,差异有统计学意义(P<0.05);治疗后2组患者SBP、DBP水平较治疗前均显著降低,且观察组SBP、DBP水平较对照组降低更明显,差异有统计学意义(P<0.05)。结论采用氨氯地平联合缬沙坦治疗高血压能够有效控制患者血压水平,提高临床疗效,安全性高,值得临床上应用。
Objective To observe the clinical efficacy of amlodipine combined with valsartan in the treatment of hypertension. Methods A total of 102 hypertensive patients admitted from July 2014 to July 2015 in our hospital were randomly divided into observation group (n = 51) and control group (n = 51). The control group was treated with valsartan. The observation group was treated with amlodipine on the basis of the control group, and the antihypertensive effects of the two groups were compared. Results After 4 weeks of treatment, the total effective rate in the observation group was 98.04%, which was significantly higher than that in the control group (86.27%, P <0.05). The SBP and DBP levels in the two groups were significantly lower than those before treatment The SBP and DBP levels in the observation group were significantly lower than those in the control group (P <0.05). Conclusion The combination of amlodipine and valsartan in the treatment of hypertension can effectively control the blood pressure of patients and improve the clinical curative effect, which is safe and worthy of clinical application.