目的　了解精索静脉曲张 (varicocele,VC)患儿的免疫功能状态 ,为所致不育提供参考资料。方法　采取 17例 9～ 12岁VC患儿外周静脉血 ,进行T淋巴细胞亚群、免疫球蛋白、补体免疫、红细胞免疫等常规检测。随机选择 17例年龄相同的健康男孩为对照组 ,同法检测。结果　VC患儿外周静脉血多项免疫指标值均低于对照组 ,其中以T淋巴细胞亚群、免疫球蛋白检测值差异有极显著性意义。结论　VC患儿机体免疫功能降低 ,可能是破坏血睾屏障的原因之一。 Objective To understand the immune status of children with varicocele (VC) and provide references for infertility. Methods Peripheral venous blood was collected from 17 children aged 9-12 years with VC, and T lymphocyte subsets, immunoglobulin, complement immunization and erythrocyte immunization were routinely detected. Seventeen healthy boys of the same age were randomly selected as the control group and tested in the same way. Results The multiple immunological parameters of peripheral venous blood in VC children were lower than those in the control group. Among them, the difference of T lymphocyte subsets and immunoglobulins was significant. Conclusions The reduction of immune function in VC children may be one of the reasons of damaging the blood-testis barrier.