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根据含32 P复合新型材料应用于内辐射治疗肿瘤的设想 ,以非标P模拟32 P ,用IR、接触角测定、复钙时间测试等方法研究了Ca3(PO4) 2 和Ca5(PO4) 3(OH)粉末的表面处理的效果、泄漏情况及血液相容性 结果表明 :Ca3(PO4) 2 和Ca5(PO4) 3(OH)粉末经硅烷偶联剂KH - 570处理后 ,表面形成偶联剂膜 ,有效提高粉末的疏水性 ,并明显降低P在水中的溶出量 ;同时可以提高粉末的血液相容性 ;当KH - 570溶液的浓度为 1 5%～ 2 0 % ,且KH - 570用量是粉末的 2phr时 ,表面处理的效果较佳
According to the idea of using 32 P composite new materials in the treatment of tumors by internal radiation, the non-standard P-32 P was used to study the effects of Ca3 (PO4) 2 and Ca5 (PO4) 3 (OH) powder, the results of leakage and blood compatibility showed that the surface of Ca3 (PO4) 2 and Ca5 (PO4) 3 (OH) powders were treated with silane coupling agent KH - 570, It can effectively improve the hydrophobicity of powder and significantly reduce the amount of P dissolved in water. At the same time, the hemocompatibility of powder can be improved. When the concentration of KH - 570 solution is 15% ~ 20% and KH - 570 The amount of powder is 2phr, the surface treatment is better