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红霉素在目前使用中,一般认为是一种最安全的抗菌素,然而它可引起可逆转性的感音性神经性听力下降。作者报告1例18岁的女孩,并与过去报道的6例作了对比。病例患者女性,18岁,患慢性肾病并尿毒症入院。血肌酐为10.4mg/100毫升,电解质正常。口服红霉素盐Steacate治疗,每天量4g,共24天。在治疗过程中,除红霉素引起的常见的胃肠症状外,于用药第9天出现耳鸣、听力下降、电测听
Erythromycin is currently considered to be one of the safest antibiotics in use, yet it causes reversible, sensorineural hearing loss. The authors report a 18-year-old girl and compared it with 6 cases reported in the past. Case Patient Female, 18 years old, suffering from chronic kidney disease and uremia admitted to hospital. Serum creatinine was 10.4 mg / 100 ml, electrolytes normal. Oral erythromycin salt Steacate treatment, the amount of 4g, a total of 24 days. In the course of treatment, in addition to common gastrointestinal symptoms caused by erythromycin, tinnitus appeared on the 9th day of medication, hearing loss, electric audiometry