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子宫内膜异位症是目前妇科常见病、多发病,占育龄妇女的15‰,属妇科临床难治之病。症状有血尿、便血等,对妇女身心健康造成极大伤害。笔者自90年代初起,试用雷公藤多甙(GTW)治疗内异症,开展对该药物的临床疗效观察与作用机理的实验研究,获得启示。临床观察发现GTW30mg/d与丹那唑600mg/d(均服药6个月)西药治疗内异症获得相仿疗效的结果,有效率分别为70%和72%。GTW治疗内异症的疗效是肯定的,但其作用机理还待进一步研究,临床观察也还需不断探索。故选用时要谨慎。
Endometriosis is the common gynecological diseases, frequently-occurring disease, accounting for 15 ‰ of women of childbearing age, is a gynecological clinical refractory disease. Symptoms such as hematuria and hematochezia cause great harm to women’s physical and mental health. The author since the early 90s, the trial of tripterygium glycosides (GTW) treatment of endometriosis, to carry out the clinical observation of the drug efficacy and experimental mechanism of action, access to enlightenment. Clinical observation found that GTW30mg / d and 600mg / d of danazol (both taking 6 months) Western medicine treatment of endometriosis results were similar, the effective rates were 70% and 72%. GTW treatment of endometriosis efficacy is yes, but its mechanism of action needs further study, clinical observation also need to continue to explore. Therefore, when used to be careful.