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目的:提高对胰腺神经鞘瘤影像学特征的认识。方法:回顾性分析1989年1月至2019年1月间海军军医大学附属长海医院收治的胰腺神经鞘瘤患者的临床资料，检索中英文数据库相关文献，对该肿瘤相关临床表现及影像学特征进行分析。结果:共84例患者，其中长海医院3例，文献报道81例。发病年龄17～78岁，平均55岁。男性30例，女性54例，主要症状为腹痛或体检发现胰腺占位病变。肿瘤主要位于胰腺头部，最长径1～18 cm，平均4.6 cm，呈实性、囊性、囊实性，以囊性变多见，胰腺周围组织界限清楚，常可见半透明的神经外膜和纤维组成的包膜。15例行内镜超声下细针穿刺术，诊断正确率为73.3%(11/15)。CT检查无特征性表现。35例行MRI检查，其中12例资料完整，其MRI靶征为肿瘤组织在Tn 1WI呈完全低信号，Tn 2WI呈部分低信号、部分高信号；Tn 1增强后可见与Tn 2WI区域完全相反的信号特征，即Tn 2WI低信号部分逐渐强化，呈高信号，而高信号部分未见强化，呈低信号。n 结论:胰腺神经鞘瘤病例罕见，其MRI的靶征有助于提高对该肿瘤的术前诊断。“,”Objective:To improve the current understanding on the imaging features of pancreatic schwannoma.Methods:Clinical data of pancreatic schwannoma patients admitted in Changhai Hospital affiliated with Navy Medical University from January 1989 to January 2019 were retrospectively analyzed, related literature on pancreatic schwannomas was retrieved through the Chinese and English database, and clinical and imaging features of pancreatic schwannoma were analyzed.Results:A total of 84 cases were analyzed, including 3 cases of pancreatic schwannomas in Changhai hospital, and 81 cases reported in the literature. The age of onset was 17-78 years old, with an average of 55 years. There were 30 males and 54 females. The main symptoms were abdominal pain or the detection of pancreatic mass n via body check. Pancreatic schwannoma was mainly in pancreatic head, and the lesion has a long diameter of 1-18 cm with an average of 4.6 cm, which can be solid, cystic (most frequent) and cystic-solid. The border of the lesion from the normal tissue was clear, and semi-transparent capsule composed of neural external membrane and fiber were often found. 15 patients underwent endoscopic ultrasonography guided fine needle aspiration, and diagnostic accuracy was 73.3%(11/15). No typical findings for pancreatic schwannoma was detected on CT. MRI was performed in 35 cases, and 12 cases had complete data. The characteristics of target sign were tumor tissue in completely low signal at Tn 1WI, and in partially low signal and partially high signal at Tn 2WI, and completely opposite signal characteristics of Tn 2WI area after Tn 1 enhancement, referring to the finding that low Tn 2WI signal part was gradually enhanced to be high signal, but high signal part was not enhanced and in low signal.n Conclusions:Pancreatic schwannoma is rare, and its target signs by MRI have imaging features which can help to improve the preoperative diagnosis.