目的:研究探讨采用综合疗法治疗大龄儿童及青少年弱视的疗效。方法:对85例8123眼7～17岁的弱视患者在专业医师的指导下,采用综合法进行治疗,分别按年龄、弱视类型和程度、注视性质对其疗效作统计分析。结果:治愈87眼(治愈率70·73%)进步31眼,总有效率95·53%。7～12岁组78眼中治愈62眼(79·50%),13～17岁组45眼治愈25眼(55·30%),两组疗效差异有显著性。中心注视患者93眼治愈76眼(81·72%),旁中心注视30眼治愈11眼(36·77%),差异具有显著性意义(P<0·01)。屈光不正性弱视76眼治愈61眼(80·28%),屈光参差性弱视26眼治愈19眼(68·46%),斜视性弱视21眼治愈7眼(33·33%),疗效差异具有显著性意义(P<0·01)。轻度弱视56眼治愈52眼(94·64%),疗效与中重度弱视比较差异具有显著性意义(P<0·01)。结论:综合疗法治疗大龄儿童及青少年弱视疗效肯定,青少年弱视存在着可治愈性,不应轻易放弃治疗,其疗效与弱视类型、程度及注视性质有关。 Objective: To study the effect of comprehensive therapy on amblyopia in older children and adolescents. Methods: A total of 85 patients (8123 eyes) with amblyopia of 7 to 17 years old under the guidance of professional physicians were treated with the integrated method. Statistical analysis was made on their therapeutic effects according to their ages, types and degrees of amblyopia and gaze. Results: The cure rate of 87 eyes (cure rate 70.73%) was 31 eyes, the total effective rate was 95.53%. In the 7 ~ 12 age group, 62 eyes (79 · 50%) were cured in 78 eyes, and 25 eyes (55 · 30%) were cured in 45 eyes in 13 ~ 17 age group. There was significant difference between the two groups. There were 76 eyes (81.72%) cured in 93 eyes of the center and 11 eyes (36.77%) in 30 eyes of the center, the difference was significant (P <0.01). Sixty-seven eyes (80.28%) were cured with refractive amblyopia, 19 eyes (68.46%) with anisometropic amblyopia, and seven eyes (33.33%) with strabismic amblyopia. The difference was significant (P <0.01). Mild amblyopic 56 eyes were cured 52 eyes (94.64%), the effect of moderate and severe amblyopia was significantly different (P <0.01). Conclusion: Comprehensive treatment of the treatment of amblyopia in older children and adolescents affirmed a sure, juvenile amblyopia exist curative, should not give up treatment, its efficacy and the type of amblyopia, degree and gaze nature.