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目的:探讨乳腺癌患者乳腺外器官可疑恶性病变穿刺活检的价值。方法:对35例影像学检查怀疑乳腺外器官有恶性病变的病灶行CT引导下经皮细针穿刺活检术,并分析穿刺活检病理结果及其临床意义。结果:所有病例均一次穿刺成功。35个病灶穿刺明确为恶性30个,穿刺活检阳性预测值为100.0%(30/30),敏感性为85.7%(30/35)。23个活检确诊为腺癌病灶的免疫组化标记分析诊断为肺原发性腺癌5例,转移性乳腺癌14例,无法确定转移或原发4例。在14例转移性乳腺癌病例中,ER、PR及HER-2均为阴性病例3例。结论:乳腺癌患者行乳腺外器官可疑恶性病变穿刺活检是获取病理学确诊依据的有效手段,可以满足临床对病变良恶性定性及恶性病变组织学分型和免疫组化诊断的要求,其安全可靠,值得推广。
Objective: To investigate the value of biopsy of suspicious malignant lesions of extramammary breast in patients with breast cancer. Methods: Percutaneous fine needle aspiration biopsy under CT guidance was performed in 35 cases of lesions suspected to have malignant lesions outside the breast. The biopsy results were analyzed and their clinical significance was analyzed. Results: All cases were successfully punctured. 35 lesions were clearly malignant 30, biopsy positive predictive value was 100.0% (30/30), the sensitivity was 85.7% (30/35). 23 biopsies diagnosed as adenocarcinoma lesions by immunohistochemical analysis of the diagnosis of lung adenocarcinoma in 5 cases, metastatic breast cancer in 14 cases, can not be confirmed in 4 cases of metastasis or primary. In 14 cases of metastatic breast cancer, ER, PR and HER-2 were negative cases in 3 cases. Conclusion: The biopsy of suspicious malignant lesions of extramammary organs in breast cancer patients is an effective means to obtain the basis of pathological diagnosis, which can meet the clinical requirements for histological classification and immunohistochemical diagnosis of benign and malignant lesions. The method is safe and reliable, Worth promoting.