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Harmperl(1934年)和Winkelstein(1935年)分别描述反流性食管炎(GERD)的病理和临床表现。特别是内镜广泛开展以来,发病率逐年有所增加。GERD药物治疗,疗效不佳,复发率高。本文研究的目的是观察普瑞博思与思密达联合治疗对缓解GERD的反流症状及治疗GERD的疗效。 1 资料与方法 1.1 病例选择:湖北省武汉市第三医院、第七医院内科共193例经内镜确诊为GERD患者,其年龄为18~75岁(男99例,女94例)。有反流症状(返酸、返食、嗳气、烧心、吞咽疼痛等),且排除有食管狭窄、肿瘤、消化性溃疡、炎症性肠病、肠梗阻、妊娠妇女,1周前服用制酸剂者为当选病例。
Harmperl (1934) and Winkelstein (1935) describe the pathology and clinical manifestations of reflux esophagitis (GERD). Especially since the extensive implementation of endoscopy, the incidence has increased year by year. GERD drug therapy, poor efficacy, high recurrence rate. The purpose of this study is to observe the combination of prepulf and metmin combined to relieve reflux symptoms of GERD and to treat GERD. 1 Materials and Methods 1.1 Case Selection: Third Hospital of Wuhan City, Hubei Province, a total of 193 cases of endoscopic diagnosis of GERD 193 patients, aged 18 to 75 years (99 males and 94 females). A reflux symptoms (back to acid, feeding, belching, heartburn, swallowing pain, etc.), and exclude esophageal stricture, cancer, peptic ulcer, inflammatory bowel disease, intestinal obstruction, pregnant women, taking antacids 1 week ago For the elected case.