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用原子吸收法测定372 名小学生的血铅(pbB) ,同时测定红细胞游离原卟啉( FEP) 、血中5羟色胺(5HT) 、多巴胺( DA) 和去甲肾上腺素( NE) ;采用 WHO 提供的神经行为核心测试组合测定神经行为;Conners 量表测多动。共20 项指标,分别以血铅5 、10 、15 、25μg/dl 为界划分成高铅组与低铅组,比较各指标差异。结果表明:10μg/dl 及以上界值的两组间皆有8 ～11 项差异无显著(P< 0-05 或< 0-01) ,以5μg/dl 为界两组间各指标差异无显著性。而血铅低于10μg/dl 、FEP≥50μg/dl时最大反应时延长( P< 0-05) ,视觉记忆缩短(P < 0-05) ,因而,pbB≥10μg/dl 者或BPb < 10μg/dl、FEP≥50μg/dl 的小学生应做为防治干预的重点人群
The blood lead levels (pbB) of 372 primary school students were measured by atomic absorption spectrometry. Free erythrocyte protoporphyrin (FEP), serotonin 5HT, dopamine (DA) and norepinephrine (NE) The neurobehavioral core test combination provided by WHO was used to determine the neurological behavior; the Conners scale was used to measure the motor activity. A total of 20 indicators, respectively, the blood lead 5, 10, 15, 25μg / dl delimited into high lead group and low lead group, compare the differences of each index. The results showed that there was no significant difference (P <0-05 or <0-01) between 8 and 11 in the two groups of 10μg / dl and above, and there was no significant difference between the two groups in the range of 5μg / dl Sex. (P <0-05), visual memory shortened (P <0-05). Therefore, those with pbB≥10μg / dl or BPb <10μg / dl, FEP ≥ 50μg / dl of primary students should be the focus of prevention and treatment of intervention groups