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本文旨在证明A亚型呼吸道合胞病毒(RSV-A)G蛋白130-230氨基酸区(G2Na)与链球菌G蛋白的血清白蛋白结合区(BB)融合(BBG2Na)后免疫原性增强,从而可作为候选RSV疫苗。 给6~8周龄BALB/c小鼠皮下注射1剂不同浓度的 G2Na或 BB
This article aims to demonstrate that the immunogenicity of the RSV-A G protein 130-230 amino acid region (G2Na) after fusion with the serum albumin binding region (BB) of Streptococcus G protein (BBG2Na) Which can be used as candidate RSV vaccine. BALB / c mice aged 6-8 weeks were injected subcutaneously with 1 dose of G2Na or BB at different concentrations