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近年来,在制剂技术发展中值得引人注目的是各个争夸各自形形式式的包衣技术,这方面的专利件数也在不断地增加着。关于包衣的历史,可追溯到十世纪左右出现的用车前草粘液包衣丸这一史实,十九世纪之后出现了各种各样的包衣技术,一般以糖衣、火棉胶和角蛋白等用来包薄膜衣。十九世纪后半叶至二十世纪这段时间的佼佼者是糖衣,但这种工艺既费时又需要熟练的手艺,需要提倡的是薄膜包衣技术。1970年由于邻苯二甲酸醋酸纤维素(CAP)和羟丙基甲基纤维素(HPMC)等薄膜材料和新型包衣机
In recent years, what deserves our attention in the development of formulation technology is that various kinds of coating technologies are extolled each other, and the number of patents in this field is constantly increasing. With regard to the history of the coating, which dates back to the tenth century or so Ephesus mucosa coated pills this historical facts, after the nineteenth century there have been a variety of coating techniques, usually sugar-coated, collodion and angle Proteins are used to coat thin films. The second half of the nineteenth century to the twentieth century, the leader in this period is sugar-coated, but this process is time-consuming and require skilled craftsmanship, the need to promote the film coating technology. 1970 due to cellulose acetate phthalate (CAP) and hydroxypropyl methyl cellulose (HPMC) and other film materials and a new type of coating machine