例1、例2:女性,19岁,为双胞胎。病人长期大便便血,为新鲜血便。有间歇性脓血便。有时出现腹痛、腹胀、腹泻。其中,有1例出现口唇、手指色素沉着。结肠镜检查所见:息肉呈弥漫分布,均为直径约0.2~1.0 cm大小不等之葡萄状息肉。均行全结肠切除术。术后病理组织学检查证实为结肠多 Case 1 and Case 2: Female, 19 years old, twins. The patient’s long-term stool bloody stool is fresh bloody stool. There is intermittent pus and blood. Abdominal pain, bloating, and diarrhea sometimes occur. Among them, there was 1 case of pigmentation of the lips and fingers. Colonoscopy revealed: polyps were diffusely distributed, and all of them were grape-like polyps ranging in size from about 0.2 to 1.0 cm in diameter. All patients underwent total colectomy. Postoperative histopathological examination confirmed colonic