论文部分内容阅读
目的探讨喉气管腺样囊性癌的临床特点、治疗方法及预后。方法回顾性分析10例行喉气管腺样囊性癌的临床资料,根据UICC 2002年TNM分期标准,喉腺样囊性癌T1N0M01例,T2N0M01例,T3N0M03例;根据Bhattacharw a分期,气管腺样囊性癌T1N0M01例,T2N0M03例,T3N0M01例。10例患者临床上以喉痛、声嘶、咳嗽及进行性呼吸困难伴喘鸣等为主要表现形式,采取手术加术后辅助放疗的治疗模式。喉腺样囊性癌以喉全切除术和喉部分切除术为主,气管腺样囊性癌以气管袖状切除加端端吻合术为主。术后辅助放疗,采用调强放疗方式,总剂量60～70 Gy。结果 10例患者术后愈合好,无并发症,随访时间为2个月～7年不等,所有病例均未见局部复发及远处转移。结论喉气管腺样囊性癌临床上以进行性呼吸困难伴喘鸣、咳嗽及声嘶为主,纤维喉镜检查有利于早期发现。该病颈淋巴转移率低,预后较好。根治性切除加术后辅助放疗是治疗喉气管腺样囊性癌的最佳方法。
Objective To investigate the clinical features, treatment and prognosis of laryngotracheal adenoid cystic carcinoma. Methods The clinical data of 10 cases of laryngeal tracheal adenoid cystic carcinoma were retrospectively analyzed. According to the UICC 2002 TNM staging criteria, there were 01 cases of laryngeal cystic carcinoma T1N0M01, T2N0M01 and T3N0M03. According to the Bhattacharw a staging, the tracheal adenoid cyst T1N0M01 cases of cancer, T2N0M03 cases, T3N0M01 cases. Ten patients were clinically sore throat, hoarseness, cough and progressive dyspnea with wheezing as the main form of surgery and postoperative adjuvant radiotherapy treatment mode. Laryngeal-like cystic carcinoma with laryngectomy and laryngectomy based, tracheal adenoid cystic carcinoma with tracheal sleeve resection plus end-based anastomosis. Postoperative adjuvant radiotherapy, using intensity-modulated radiation therapy, the total dose of 60 ~ 70 Gy. Results 10 cases of postoperative healing, no complications, follow-up time ranging from 2 months to 7 years, all cases were no local recurrence and distant metastasis. Conclusions Laryngeal tracheal adenoid cystic carcinoma is clinically characterized by progressive dyspnea with wheezing, coughing and hoarseness. Fibrolaryngoscopy is beneficial for early detection. The disease cervical lymphatic metastasis rate is low, the prognosis is good. Radical resection plus adjuvant radiotherapy is the best way to treat laryngotracheal adenoid cystic carcinoma.