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目的探讨高原地区重症急性高原病是否存在多器官功能障碍(MODS)。方法对我院1971年—1997年收治的1200例高原肺水肿(HAPE)中检出的65例合并脑水肿患者病历资料进行系统性分析。结果高原地区重症急性高原病患者普遍存在着MODS,本组65例患者从病例资料反映少则出现3个系统或器官功能障碍,多则达6个系统或器官功能障碍,其中3例死亡病例均存在6个器官功能障碍,并以肺、脑、心、肾功能障碍为主,尤其是脑、肾功能衰竭尤为突出。65例病例中器官功能障碍出现及出现频率由大到小依次为肺、脑、心脏、肾脏、眼、胃肠等。结论高原地区重症急性高原病患者普遍存在着MODS,在临床治疗中应加强重要器官功能的保护。
Objective To investigate the presence of multiple organ dysfunction (MODS) in severe acute mountain sickness in the plateau. Methods The data of medical records of 65 patients with cerebral edema detected in 1,200 cases of high altitude pulmonary edema (HAPE) admitted from 1971 to 1997 in our hospital were systematically analyzed. Results There was a prevalence of MODS in patients with severe acute mountain sickness in the plateau area. The 65 patients in this group showed three system or organ dysfunction as many as six system or organ dysfunction, of which 3 died There are six organ dysfunction, and lung, brain, heart and kidney dysfunction, especially brain and kidney failure is particularly prominent. The incidence and frequency of organ dysfunction in 65 cases were lung, brain, heart, kidney, eye, gastrointestinal and so on in descending order. Conclusion MODS prevalence is found in patients with severe acute altitude sickness in the plateau area, and the protection of vital organ function should be strengthened in the clinical treatment.