应用生物学方法检测了２６例格林－巴利综合征（ＧＢＳ）患者血清及脑脊液中白细胞介素６（ＩＬ－６）含量。结果显示：ＧＢＳ患者血清及脑脊液中ＩＬ－６水平明显高于正常对照组（Ｐ＜０．００１）；血清中ＩＬ－６含量与脑脊液中ＩＬ－６含量无相关性；血清中ＩＬ－６含量与血清免疫球蛋白含量无相关性；但血清免疫球蛋白水平明显高于正常对照组（Ｐ＜０．０１）。提示Ｂ淋巴细胞在ＧＢＳ免疫机制中可能处于激活状态 The levels of interleukin-6 (IL-6) in serum and cerebrospinal fluid (CSF) of 26 patients with Guillain-Barre syndrome (GBS) were detected by using biological methods. The results showed that the level of IL-6 in serum and cerebrospinal fluid of patients with GBS was significantly higher than that of the normal control group (P <0.001). There was no correlation between IL-6 in serum and IL-6 in cerebrospinal fluid (IL-6) And serum immunoglobulin content no correlation; but serum immunoglobulin levels were significantly higher than the normal control group (P <0.01). Suggesting that B lymphocytes may be activated in the GBS immune mechanism