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目的 探讨救治有机磷农药中毒时阿托品效应低下的原因及对策。方法 根据患者入院时的临床表现 ,应用阿托品后的效应及相应急救方案 ,总结分析抢救 12 0例重度有机磷农药中毒时应用阿托品效应低下的影响因素及转归。结果 未达到阿托品化的 3 2例均死亡 ,死亡率 10 0 % ;达到阿托品化的 68例患者中 ,死亡率 41.1% ;出现阿托品中毒者 2 0例 ,死亡率 60 % ;总死亡率 60 % (72 /12 0 )。结论 有机磷农药中毒救治中阿托品效应低下者预后极差 ,除受毒物品种、中毒程度、就诊时间影响外 ,还受残毒继续吸收 ,严重并发症 ,阿托品与复能剂使用不当 ,混合性中毒等综合因素影响。须及时有效的采取应急措施
Objective To explore the causes and countermeasures of low effect of atropine on organophosphorus pesticide poisoning. Methods According to the clinical manifestations of patients on admission, the effects of atropine and the corresponding emergency treatment programs were analyzed and summarized. The influencing factors and prognosis of lowering atropine in 12 cases of severe organophosphorus pesticide poisoning were summarized and analyzed. Results 32 cases of atropine were not killed, the mortality rate was 10%; 68 cases of atropine in the mortality rate of 41.1%; 20 cases of atropine poisoning, the mortality rate of 60%; the total mortality rate of 60% (72/12 0). Conclusion The prognosis of patients with low dose of atropine in organophosphorus pesticide poisoning treatment is extremely poor. In addition to being affected by the variety of poison, the degree of poisoning and the time of visiting, organophosphorus pesticide poisoning continues to be absorbed by residual poison, serious complication, improper use of atropine and co-agent, mixed poisoning Comprehensive factors affect. Must promptly and effectively take emergency measures