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大量证据表明,纤溶系统失衡与缺血性心血管事件的发生有关,参与心血管发病机制。肾素-血管紧张素系统控制纤溶系统,通过药理学干预抑制AngⅡ活性,可改善纤溶平衡,降低心血管事件的发生。
Numerous evidences show that fibrinolytic system imbalances are associated with the occurrence of ischemic cardiovascular events and are involved in cardiovascular pathogenesis. The renin-angiotensin system controls the fibrinolytic system and inhibits AngII activity through pharmacological interventions to improve the fibrinolytic balance and reduce the occurrence of cardiovascular events.