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目的：观察三七皂甙治疗后对休克兔肝脏超微结构的保护作用。方法：家兔２０只，随机等分为对照组与治疗组。钳夹肠系膜上动脉制成ＳＭＡＯ休克模型。治疗组静注三七根总皂甙２００ｍｇ／ｋｇ，对照组静注等量生理盐水。结果：治疗组存活时间明显延长，并改善ＭＡＰ。休克期间肝细胞的破坏明显减轻，与对照组比较肝窦内枯否氏细胞功能较为活跃。结论：三七皂甙对肝脏有保护作用，对延长ＳＭＡＯ休克兔的存活时间起到了重要作用。
Objective: To observe the protective effect of Panax notoginseng saponin on liver ultrastructure of shock rabbits. Methods: Twenty rabbits were randomly divided into control group and treatment group. The upper mesenteric artery was clamped to make the SMAO shock model. The treatment group received intravenous injection of Panax notoginseng saponin 200 mg/kg, and the control group received intravenous saline. Results: The survival time of the treatment group was significantly prolonged and MAP was improved. The destruction of hepatocytes during shock was significantly reduced, and the function of Kupffer cells in hepatic sinusoids was more active than that of the control group. Conclusion: Panax notoginseng has a protective effect on the liver and plays an important role in prolonging the survival time of SMAO shock rabbits.