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目的 探索心肌肌钙蛋白T(cTnT)在川崎氏病早期的意义。方法 应用ELISA方法对25例川崎氏病早期的病人血清中cTnT、CPK、CKMB进行监测,观察其对心肌缺氧的敏感性,并选择cTnT与心脏扇扫提示的冠状动脉改变情况进行对比。结果 25例中14例cTnT,1例CPK,1例CKMB升高,21例冠状动脉有改变,冠状动脉无改变4例中2例cTnT升高且同时伴有心电图改变。结论 ①在川崎氏病早期cTnT的敏感性高于CPK和CKMB;②CTnT可以提示一些扇扫中无法发现的冠状动脉异常所致的心肌缺血
Objective To explore the significance of cardiac troponin T (cTnT) in the early stage of Kawasaki disease. Methods Serum levels of cTnT, CPK and CKMB in 25 patients with early Kawasaki disease were measured by ELISA. The sensitivity to myocardial hypoxia was observed. The changes of cTnT and coronary artery were also compared. Results Among the 25 cases, cTnT was increased in 14 cases, CPK in 1 case and CKMB increased in 1 case. There were 21 cases of coronary artery and 2 cases of coronary artery were unchanged. Among them, 2 cases had elevated cTnT accompanied with electrocardiogram changes. Conclusions ① The sensitivity of cTnT in early stage of Kawasaki disease is higher than that of CPK and CKMB. ②CTnT can prompt the myocardial ischemia