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目的:探讨生理因素对受照的部分或完全乏氧的肿瘤细胞DNA链断裂和DNA-蛋白质交联(DPCs)的诱导和修复的影响。方法:分别选取处于指数生长期(pH6.6~6.7和7.2~7.3,3天)和坪期(pH6.8~6.9,葡萄糖几乎耗尽,5天)的9L大鼠脑肿瘤细
Objective: To investigate the effects of physiological factors on DNA strand breaks and DNA-protein cross-linking (DPCs) induction and repair of irradiated partially or completely hypoxic tumor cells. METHODS: 9L in the exponential growth phase (pH 6.6-6.7 and 7.2-7.3, 3 days) and ping phase (pH 6.8-6.9, glucose almost exhausted, 5 days) were selected. Rat brain tumor fine