心得安为1960年合成的β受体阻滞剂,1964年用于临床。Turaer1965年首先将它用来治疗甲状腺机能亢进症(以下简称甲亢),证明在减慢病人心率方面有明显作用。它能迅速控制甲亢的周围症状,如心动过速、震颤、焦虑不安等。近十多年来被广泛作为抗甲状腺药的辅助治疗,如甲亢的术前准备,甲亢危象的紧急处理等。其作用不改变甲状腺的机能状态,只是减轻交感神经的兴奋状态, Adams for the 1960 synthesis of β-blockers, 1964 for clinical use. Turaer was first published in 1965 to prove that it has a significant role in slowing the patient’s heart rate. It can quickly control the surrounding symptoms of hyperthyroidism, such as tachycardia, tremors, anxiety and so on. Nearly a decade has been widely used as adjuvant anti-thyroid drugs, such as preoperative preparation of hyperthyroidism, hyperthyroidism crisis emergency treatment. Its role does not change the functional status of the thyroid, just to reduce the excitement of the sympathetic,