最近报道从反复感染发作的病人体内常分离到青霉素耐受性突变株。这类细菌的特点是允许青霉素进入细胞,细菌本身含有正常的青霉素结合蛋白,能与外来的青霉素结合,其后细菌生长受到抑制,减少活性,但不被溶解。这种耐受(Tolerance)现象属于细菌耐药性的范畴。 It has recently been reported that penicillin-resistant mutants are often isolated from patients with recurrent infections. Such bacteria are characterized by allowing penicillin into the cell, the bacteria themselves contain normal penicillin-binding protein, can be combined with the external penicillin, followed by bacterial growth inhibition, reduce the activity, but not be dissolved. This Tolerance phenomenon belongs to the category of bacterial resistance.