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神经血管单元(NVU)概念的提出将缺血后脑保护的目标从过去单一的神经保护提升到对神经细胞、血管及胶质等整体结构式的保护,为缺血性脑损伤的基础研究及治疗提供了新方向。中药具有多组分、多靶点、多环节、多途径的全面保护及整体调节的优势和特点,正好符合NVU治疗策略的要求。文章主要对具有神经血管单元保护作用的中药及复方研究进展进行综述,以期为今后中药治疗缺血性脑卒中的临床研究提供一定参考。
The concept of neurovascular unit (NVU) promotes the goal of ischemic brain protection from the single neuroprotection in the past to the protection of the overall structure of nerve cells, blood vessels and glia, provides basic research and treatment for ischemic brain injury A new direction. Traditional Chinese medicine has multi-component, multi-target, multi-link, multi-channel comprehensive protection and overall adjustment advantages and characteristics, just in line with NVU treatment strategy requirements. The article mainly reviews the research progress of traditional Chinese medicine and compound with neurovascular unit protection in order to provide some reference for the clinical study of traditional Chinese medicine in the treatment of ischemic stroke.