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目的探讨代谢综合征(MS)与白细胞介素6(IL-6)、高敏C反应蛋白(hsCRP)的关系。方法随机抽取MS患者195例为MS组,120例健康人群为对照组进行研究,采用ELISA法检测IL-6,用免疫比浊法检测hsCRP。结果MS组血清IL-6[(1.98±0.43)比(1.71±0.61)ng/L,P<0.01]、hsCRP[(0.46±0.14)比(0.19±0.17)mg/L,P<0.05]水平高于对照组;随着MS组分数目增加,IL-6、hsCRP水平均逐渐升高,在调整了年龄后,hsCRP与MS密切相关。结论代谢综合征与炎症密切相关,代谢综合征患者IL-6、hsCRP水平升高。
Objective To investigate the relationship between metabolic syndrome (MS) and interleukin-6 (IL-6) and high-sensitivity C-reactive protein (hsCRP) Methods A total of 195 patients with MS were randomly divided into MS group and 120 healthy subjects as control group. IL-6 was detected by ELISA and hsCRP by immunonephelometry. Results The serum levels of IL-6 in MS group were significantly higher than those in the control group (1.98 ± 0.43 vs 1.71 ± 0.61 ng / L, P <0.01), hsCRP [(0.46 ± 0.14) vs (0.19 ± 0.17) mg / Which was higher than that of the control group. As the number of MS components increased, the levels of hsCRP and IL-6 gradually increased. After adjusting for age, hsCRP was closely related to MS. Conclusion Metabolic syndrome is closely related to inflammation, and the levels of IL-6 and hsCRP in patients with metabolic syndrome are increased.